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Does rheumatoid arthritis affect your muscles? Some of the most common symptoms reported by people with rheumatoid arthritis are: Joints are supported by surrounding muscles, ligaments and tendons, but, with RA, these will weaken and no longer stabilize joints. This causes intense pain and joint damage as a result. How long does it take for Humira to work for psoriatic arthritis? In a clinical study of adult patients with active psoriatic arthritis using HUMIRA, some patients experienced an improvement in signs and symptoms in as soon as 2 weeks. The majority of patients experienced a significant reduction in the joint symptoms of psoriatic arthritis in just 12 weeks. Why does psoriatic arthritis make you so tired? "Proteins called cytokines that are released during inflammatory reactions can cause fatigue, but also contributing can be conditions that are common among people with psoriatic arthritis, including anemia, obesity, diabetes, depression and sleep problems."
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